- Scientific research has allowed us to better understand Boldo Leaf’s mechanism of action. It contains boldine which helps secretion and reduction of bile, allowing a better food digestion. Boldo has a long history of use as a liver tonic and in supporting gallstones by the indigenous people of Chile. Boldo contains several types of primary constituents, including volatile oils (e.g., ascaridole, eucalyptol), flavonoids, and alkaloids. Boldine, which constitutes about one-fourth of the total nu
